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#56313 - 09/30/08 03:49 AM Re: More progress @Quest [Re: mike856nj]
nervx Offline
Member

Registered: 04/16/06
Posts: 2
Quote:
There was no statistically significant
improvement in hair count reduction observed in the subjects treated with
SL017 PDT compared to IPL treatment alone at any of the IPL doses or in either
of the two hair populations studied.


frown

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#56360 - 10/01/08 05:37 PM Re: More progress @Quest [Re: nervx]
roma18 Offline
Top 20 Contributor

Registered: 09/20/06
Posts: 200
Loc: california
Are they doing more research or have terminated everything altogether?

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#56365 - 10/02/08 05:04 AM Re: More progress @Quest [Re: roma18]
chris27 Offline
Contributor

Registered: 05/11/08
Posts: 10
Photoderma claimed that they got hair reduction with their product. So I guess our only hope is Photoderma and Applisonix.

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#56421 - 10/05/08 12:14 AM Re: More progress @Quest [Re: chris27]
roma18 Offline
Top 20 Contributor

Registered: 09/20/06
Posts: 200
Loc: california
Photoderma website hasn't been updated for a long time.

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#56439 - 10/05/08 08:10 PM Re: More progress @Quest [Re: nervx]
jme1 Offline
Major Contributor

Registered: 12/25/05
Posts: 89
Originally Posted By: nervx
Quote:
There was no statistically significant
improvement in hair count reduction observed in the subjects treated with
SL017 PDT compared to IPL treatment alone at any of the IPL doses or in either
of the two hair populations studied.


frown


Please include a link to your quote. I see something different.

http://biz.yahoo.com/cnw/080911/quest_pharma_q2_reslt.html?.v=1

"Press Release Source: Quest PharmaTech Inc.


Quest PharmaTech Announces Second Quarter Results
Thursday September 11, 7:00 am ET


TSX Venture: QPT
EDMONTON, Sept. 11 /CNW/ - Quest PharmaTech Inc. (TSX-V: QPT - News), a pharmaceutical company developing and commercializing products for the treatment of cancer and dermatological conditions, today announced fiscal second quarter results for the period ended July 31, 2008.
"We made significant progress with our clinical and research programs during our second quarter," stated Pierre Vermette, Chief Financial Officer of Quest. "We also made notable improvements to our financial position, which will help us execute on our long-term business objectives."


Highlights for the quarter

- In June, the Company announced successful interim results from its
Phase I/II clinical study designed to investigate appropriate
treatment parameters for the potential use of its proprietary
compound SL017 for hair removal applications."

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#56452 - 10/06/08 06:39 AM Re: More progress @Quest [Re: jme1]
nervx Offline
Member

Registered: 04/16/06
Posts: 2
Quote:
Please include a link to your quote. I see something different


why when the news was posted a few posts back.

all your post mentions is that they were able to make progress in testing their products(no set backs) and now have a financial backing so they can continue on.

however the results for the hair removal product itself shows that it is useless at improving hair reduction over the current IPL method. in other words it failed.

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#56464 - 10/06/08 02:32 PM Re: More progress @Quest [Re: nervx]
jeffk Offline
Contributor

Registered: 10/31/06
Posts: 39
quest ist currently trying to alter conditions for the use of SL017 like pretreatment of skin etc,
under "normal" conditions there was no impact of the photosensitizer

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#56480 - 10/06/08 05:12 PM Re: More progress @Quest [Re: nervx]
jme1 Offline
Major Contributor

Registered: 12/25/05
Posts: 89
Originally Posted By: nervx
Quote:
Please include a link to your quote. I see something different


why when the news was posted a few posts back.

all your post mentions is that they were able to make progress in testing their products(no set backs) and now have a financial backing so they can continue on.

however the results for the hair removal product itself shows that it is useless at improving hair reduction over the current IPL method. in other words it failed.


My apologies for missing where you got your information. It doesn't help when you take things out of context...like you did.

Read below...Two evaluations were completed. A pretreament test which showed a statistically significant improvement in the uptake of the uptake of SL017. The second evaluation used no pre-treatment. This is the portion that you cherry picked.

" Skin Pretreatment and Follicular Uptake

Thirty healthy subjects were enrolled to evaluate the efficacy of five
different skin preparation techniques to enhance the follicular localization
of SL017. One of the five skin pretreatments demonstrated a statistically
significant improvement in both the intensity of follicular uptake of SL017
and the depth of penetration of SL017 in the hair follicle compared to the
other skin pretreatments.


Light Dose Escalation

Forty subjects with dark colored hair and 10 subjects with light colored
hair were enrolled to evaluate the safety and efficacy of combining SL017 with
increasing doses of Intense Pulse Light (IPL) ranging from 4.5J/cm(2) to
20.0J/cm(2). No skin pretreatment technique was used. No unexpected side
effects were observed at any of the light doses tested. A hair count was taken
at days 0 and 42 in each population. There was no statistically significant
improvement in hair count reduction observed in the subjects treated with
SL017 PDT compared to IPL treatment alone at any of the IPL doses or in either
of the two hair populations studied. However, 25% of the dark colored hair
population, or 10 subjects, that were non-responsive to IPL treatment
demonstrated a statistically significant reduction in hair count when treated
with SL017 PDT."

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